Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin

BACKGROUND: In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the hippocampus and cortex. Accordingly, Arc/Arg3.1 kn...

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Main Authors: Hossaini, Mehdi, Jongen, Joost LM, Biesheuvel, Karla, Kuhl, Dietmar, Holstege, Jan C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920254/
https://ncbi.nlm.nih.gov/pubmed/20653942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-43
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