Effect of codon optimization and subcellular targeting on Toxoplasma gondii antigen SAG1 expression in tobacco leaves to use in subcutaneous and oral immunization in mice

BACKGROUND: Codon optimization and subcellular targeting were studied with the aim to increase the expression levels of the SAG1(78-322 )antigen of Toxoplasma gondii in tobacco leaves. The expression of the tobacco-optimized and native versions of the SAG1 gene was explored by transient expression f...

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Bibliographic Details
Main Authors: Laguía-Becher, Melina, Martín, Valentina, Kraemer, Mauricio, Corigliano, Mariana, Yacono, María L, Goldman, Alejandra, Clemente, Marina
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920232/
https://ncbi.nlm.nih.gov/pubmed/20633272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-52
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