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Lessons from the Total Synthesis of (±) Phalarine: Insights Into the Mechanism of the Pictet–Spengler Reaction

The furanobisindole alkaloid, phalarine, possesses a unique structural framework within the alkaloid family of natural products. Our laboratory recently disclosed the racemic total synthesis of phalarine, featuring an efficient azaspiroindolenine rearrangement; this achievement is revisited in detai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Trzupek, John D., Li, Chaomin, Chan, Collin, Crowley, Brendan M., Heimann, Annekatrin C., Danishefsky, Samuel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920150/
https://ncbi.nlm.nih.gov/pubmed/20711493
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