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Hypogammaglobulinemia associated with accelerated catabolism of IgG secondary to its interaction with an IgG-reactive monoclonal IgM

Hypogammaglobulinemia due to a new pathophysiological mechanism was studied in a patient with Sjögren's syndrome, a monoclonal IgM and a mixed (IgM-IgG) cryoglobulinemia. The IgM (IgMdk) component of the cryogel possessed light chains of λ-type with highly restricted electrophoretic mobility an...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Waldmann, Thomas A., Johnson, John S., Talal, Norman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292010/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4993860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106567
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