Joint Effects of Common Genetic Variants from Multiple Genes and Pathways On the Risk of Premature Coronary Artery Disease

OBJECTIVE: To discover common variants in 6 lipid metabolic genes and construct and validate a genetic risk score (GRS) based on the joint effects of genetic variants in multiple genes from lipid and other pathobiologic pathways. BACKGROUND: Explaining the genetic basis of coronary artery disease (C...

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Bibliografische gegevens
Hoofdauteurs: Anderson, Jeffrey L., Horne, Benjamin D., Camp, Nicola J., Muhlestein, Joseph B., Hopkins, Paul N., Cannon-Albright, Lisa A., Mower, Chrissa P., Park, James J., Clarke, Jessica L., Nicholas, Zachary P., McKinney, Jason T., Carlquist, John F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919893/
https://ncbi.nlm.nih.gov/pubmed/20691829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ahj.2010.05.031
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