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Intramembranous Valine Linked to Schizophrenia Is Required for Neuregulin 1 Regulation of the Morphological Development of Cortical Neurons
Neuregulin 1 (NRG1) signaling is critical to various aspects of neuronal development and function. Among different NRG1 isoforms, the type III isoforms of NRG1 are unique in their ability to signal via the intracellular domain after γ-secretase-dependent intramembranous processing. However, the func...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919805/ https://ncbi.nlm.nih.gov/pubmed/20610754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0605-10.2010 |
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