Presynaptic Type III Neuregulin 1 Is Required for Sustained Enhancement of Hippocampal Transmission by Nicotine and for Axonal Targeting of α7 Nicotinic Acetylcholine Receptors

Both the neuregulin 1 (Nrg1) and α7 nicotinic acetylcholine receptor (α7*nAChRs) genes have been linked to schizophrenia and associated sensory–motor gating deficits. The prominence of nicotine addiction in schizophrenic patients is reflected in the normalization of gating deficits by nicotine self-...

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Detalhes bibliográficos
Main Authors: Zhong, Chongbo, Du, Chuang, Hancock, Melissa, Mertz, Marjolijn, Talmage, David A., Role, Lorna W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754770/
https://ncbi.nlm.nih.gov/pubmed/18784291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0381-08.2008
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