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The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis
The small subunit (SSU) processome is a large ribonucleoprotein that is required for maturation of the 18S rRNA of the ribosome. Recently, a missense mutation in the C-terminus of an SSU processome protein, Utp4/Cirhin, was reported to cause North American Indian childhood cirrhosis (NAIC). In this...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919705/ https://ncbi.nlm.nih.gov/pubmed/20385600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq185 |
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