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Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells

Higher expression of human telomerase reverse transcriptase (hTERT) and subsequent activation of telomerase occur during cellular immortalization and are maintained in cancer cells. To understand the mode of hTERT expression in cancer cells, we identified cancer-specific trans-regulatory proteins th...

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Detalhes bibliográficos
Main Authors: Kang, Xuedong, Chen, Wei, Kim, Reuben H., Kang, Mo K., Park, No-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919678/
https://ncbi.nlm.nih.gov/pubmed/19015635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.404
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