A Randomized Controlled Trial of Chloroquine for the Treatment of Dengue in Vietnamese Adults

BACKGROUND: There is currently no licensed antiviral drug for treatment of dengue. Chloroquine (CQ) inhibits the replication of dengue virus (DENV) in vitro. METHODS AND FINDINGS: A double-blind, randomized, placebo-controlled trial of CQ in 307 adults hospitalized for suspected DENV infection was c...

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Hlavní autoři: Tricou, Vianney, Minh, Nguyet Nguyen, Van, Toi Pham, Lee, Sue J., Farrar, Jeremy, Wills, Bridget, Tran, Hien Tinh, Simmons, Cameron P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919376/
https://ncbi.nlm.nih.gov/pubmed/20706626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000785
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