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Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle

An outstanding biological question is why tissue regeneration in mammals is limited, whereas urodele amphibians and teleost fish regenerate major structures, largely by cell cycle reentry. Upon inactivation of Rb, proliferation of postmitotic urodele skeletal muscle is induced, whereas in mammalian...

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Detalhes bibliográficos
Main Authors: Pajcini, Kostandin V., Corbel, Stephane Y., Sage, Julien, Pomerantz, Jason H., Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919350/
https://ncbi.nlm.nih.gov/pubmed/20682446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.05.022
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