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La Crosse Virus (LACV) Gc Fusion Peptide Mutants have Impaired Growth and Fusion Phenotypes, but Remain Neurotoxic
La Crosse virus is a leading cause of pediatric encephalitis in the Midwestern United States and an emerging pathogen in the American South. The LACV glycoprotein Gc plays a critical role in entry as the virus attachment protein. A 22 amino acid hydrophobic region within Gc (1066-1087) was recently...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919166/ https://ncbi.nlm.nih.gov/pubmed/20553924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.012 |
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