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La Crosse Virus (LACV) Gc Fusion Peptide Mutants have Impaired Growth and Fusion Phenotypes, but Remain Neurotoxic

La Crosse virus is a leading cause of pediatric encephalitis in the Midwestern United States and an emerging pathogen in the American South. The LACV glycoprotein Gc plays a critical role in entry as the virus attachment protein. A 22 amino acid hydrophobic region within Gc (1066-1087) was recently...

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Detalhes bibliográficos
Main Authors: Soldan, Samantha S., Hollidge, Bradley S., Wagner, Valentina, Weber, Friedemann, González-Scarano, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919166/
https://ncbi.nlm.nih.gov/pubmed/20553924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.012
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