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Role of Protein Stabilizers on the Conformation of the Unfolded State of Cytochrome c and Its Early Folding Kinetics: INVESTIGATION AT SINGLE MOLECULAR RESOLUTION

An insight into the conformation and dynamics of unfolded and early intermediate states of a protein is essential to understand the mechanism of its aggregation and to design potent inhibitor molecules. Fluorescence correlation spectroscopy has been used to study the effects of several model protein...

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Main Authors: Haldar, Shubhasis, Mitra, Samaresh, Chattopadhyay, Krishnananda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919094/
https://ncbi.nlm.nih.gov/pubmed/20538585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116673
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