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Simian Immunodeficiency Virus Infection Induces Expansion of α4β7(+) and Cytotoxic CD56(+) NK Cells

Herein we demonstrate that chronic simian immunodeficiency virus (SIV) infection induces significant upregulation of the gut-homing marker α4β7 on macaque NK cells, coupled with downregulation of the lymph node-trafficking marker, CCR7. Interestingly, in naïve animals, α4β7 expression was associated...

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Autors principals: Reeves, R. Keith, Evans, Tristan I., Gillis, Jacqueline, Johnson, R. Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919045/
https://ncbi.nlm.nih.gov/pubmed/20554780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01126-10
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