CD25(+) Natural Regulatory T Cells Are Critical in Limiting Innate and Adaptive Immunity and Resolving Disease following Respiratory Syncytial Virus Infection

Regulatory CD4(+) T cells have been shown to be important in limiting immune responses, but their role in respiratory viral infections has received little attention. Here we observed that following respiratory syncytial virus (RSV) infection, CD4(+) Foxp3(+) CD25(+) natural regulatory T-cell numbers...

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Bibliographic Details
Main Authors: Lee, Debbie C. P., Harker, James A. E., Tregoning, John S., Atabani, Sowsan F., Johansson, Cecilia, Schwarze, Jürgen, Openshaw, Peter J. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919030/
https://ncbi.nlm.nih.gov/pubmed/20573822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00796-10
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