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Attachment of Mouse Hepatitis Virus to O-Acetylated Sialic Acid Is Mediated by Hemagglutinin-Esterase and Not by the Spike Protein

The members of Betacoronavirus phylocluster A possess two types of surface projections, one comprised of the spike protein (S) and the other of hemagglutinin-esterase (HE). Purportedly, these viruses bind to O-acetylated sialic acids (O-Ac-Sias) primarily through S, with HE serving merely as recepto...

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Main Authors: Langereis, Martijn A., van Vliet, Arno L. W., Boot, Willemijn, de Groot, Raoul J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919023/
https://ncbi.nlm.nih.gov/pubmed/20538854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00566-10
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