Hit-and-Run Stimulation: a Novel Concept To Reactivate Latent HIV-1 Infection without Cytokine Gene Induction

Current antiretroviral therapy (ART) efficiently controls HIV-1 replication but fails to eradicate the virus. Even after years of successful ART, HIV-1 can conceal itself in a latent state in long-lived CD4(+) memory T cells. From this latent reservoir, HIV-1 rebounds during treatment interruptions....

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Autores principales: Wolschendorf, Frank, Duverger, Alexandra, Jones, Jennifer, Wagner, Frederic H., Huff, Jason, Benjamin, William H., Saag, Michael S., Niederweis, Michael, Kutsch, Olaf
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919022/
https://ncbi.nlm.nih.gov/pubmed/20538859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00523-10
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