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“Essential” hypernatremia due to ineffective osmotic and intact volume regulation of vasopressin secretion

A physiological explanation for sustained hyperosmolality was sought in a patient with histiocytosis. During 23 days of observation with only sodium intake regulated at 100 mEq daily, elevation (mean 310 mOsm/kg of water) and fluctuation (range 298-323) of the fasting plasma osmolality were recorded...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: DeRubertis, Frederick R., Michelis, Michael F., Beck, Nama, Field, James B., Davis, Bernard B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1971
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5101300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106489
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