Differential sensitivity to platinum-based chemotherapy in primary uterine serous papillary carcinoma cell lines with high versus low HER-2/neu expression in vitro

OBJECTIVE: To identify effective chemotherapy regimens against uterine-serous-papillary-carcinoma (USPC). STUDY DESIGN: Six UPSC, half of which overexpress HER-2/neu at 3+ level, were evaluated for growth-rate and in-vitro-sensitivity to fourteen single-agent chemotherapies and five combinations by...

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Detalhes bibliográficos
Main Authors: Cross, Sarah N., Cocco, Emiliano, Bellone, Stefania, Anagnostou, Valsamo K., Brower, Stacey L., Richter, Christine E., Siegel, Eric R., Schwartz, Peter E., Rutherford, Thomas J., Santin, Alessandro D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918912/
https://ncbi.nlm.nih.gov/pubmed/20417484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2010.02.056
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