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Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: A Randomized Clinical Trial

CONTEXT: Goal-directed resuscitation for severe sepsis and septic shock has been reported to reduce mortality when applied in the emergency department. OBJECTIVE: To test the hypothesis of noninferiority between lactate clearance and central venous oxygen saturation (ScvO(2)) as goals of early sepsi...

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Main Authors: Jones, Alan E., Shapiro, Nathan I., Trzeciak, Stephen, Arnold, Ryan C., Claremont, Heather A., Kline, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918907/
https://ncbi.nlm.nih.gov/pubmed/20179283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.158
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