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PEGylated Polyamidoamine Dendrimers with Bis-Aryl Hydrazone Linkages for Enhanced Gene Delivery

Surface modification of polyamidoamine (PAMAM) dendrimers with polyethylene glycol (PEG) often results in the decrease in their buffering capacity, which is essential for gene transfer. In this work, bis-aryl hydrazone bond, which possesses protonatable pyridine and amines, was explored as a new lin...

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Bibliografiska uppgifter
Huvudupphovsmän: Yuan, Quan, Yeudall, W. Andrew, Yang, Hu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918678/
https://ncbi.nlm.nih.gov/pubmed/20593893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm100589g
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