Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge

BACKGROUND: We have previously demonstrated protective efficacy against B. melitensis using formulations of naked DNA vaccines encoding genes ialB and omp25. The present study was undertaken to further understand the immune response generated by the protective vaccination regimens and to evaluate ca...

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Detalhes bibliográficos
Main Authors: Commander, Nicola J, Brewer, James M, Wren, Brendan W, Spencer, Stephen A, MacMillan, Alastair P, Stack, Judith A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918601/
https://ncbi.nlm.nih.gov/pubmed/20637091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-8-5
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