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Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma

BACKGROUND: Glioblastoma is the most common brain tumor in adults. The mechanisms leading to glioblastoma are not well understood but animal studies support that inactivation of tumor suppressor genes in neural stem cells (NSC) is required and sufficient to induce glial cancers. This suggests that t...

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Bibliografische gegevens
Hoofdauteurs: Evers, Patrick, Lee, Percy P, DeMarco, John, Agazaryan, Nzhde, Sayre, James W, Selch, Michael, Pajonk, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918578/
https://ncbi.nlm.nih.gov/pubmed/20663133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-384
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