Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia, a malignancy characterized by uncontrolled proliferation of virally-infected CD4+ T-cells. Hypercalcemia and bone lesions due to osteoclast-mediated bone resorption are frequently associated with...

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Autores principales: Polakowski, Nicholas, Gregory, Heather, Mesnard, Jean-Michel, Lemasson, Isabelle
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918529/
https://ncbi.nlm.nih.gov/pubmed/20653953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-61
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