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Using Cases to Strengthen Inference on the Association between Single Nucleotide Polymorphisms and a Secondary Phenotype in Genome-Wide Association Studies

Case-control genome-wide association studies provide a vast amount of genetic information that may be used to investigate secondary phenotypes. We study the situation in which the primary disease is rare and the secondary phenotype and genetic markers are dichotomous. An analysis of the association...

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Detalhes bibliográficos
Main Authors: Li, Huilin, Gail, Mitchell H., Berndt, Sonja, Chatterjee, Nilanjan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918520/
https://ncbi.nlm.nih.gov/pubmed/20583284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20495
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