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The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression

We previously described the use of a cell-based screening approach to identify small molecules that regulate adipocyte differentiation. Here we identify the amiloride derivative phenamil as an adipogenic compound. Phenamil acutely induces expression of the key transcription factor of adipogenesis, p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Won Park, Kye, Waki, Hironori, Choi, Sung-Pil, Park, Ki-Moon, Tontonoz, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918460/
https://ncbi.nlm.nih.gov/pubmed/20519739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008490
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