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The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression

We previously described the use of a cell-based screening approach to identify small molecules that regulate adipocyte differentiation. Here we identify the amiloride derivative phenamil as an adipogenic compound. Phenamil acutely induces expression of the key transcription factor of adipogenesis, p...

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Autori principali: Won Park, Kye, Waki, Hironori, Choi, Sung-Pil, Park, Ki-Moon, Tontonoz, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918460/
https://ncbi.nlm.nih.gov/pubmed/20519739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008490
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