Biochemical characterization of cholesteryl ester transfer protein inhibitors

Cholesteryl ester transfer protein (CETP) has been identified as a novel target for increasing HDL cholesterol levels. In this report, we describe the biochemical characterization of anacetrapib, a potent inhibitor of CETP. To better understand the mechanism by which anacetrapib inhibits CETP activi...

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Autori principali: Ranalletta, Mollie, Bierilo, Kathleen K., Chen, Ying, Milot, Denise, Chen, Qing, Tung, Elaine, Houde, Caroline, Elowe, Nadine H., Garcia-Calvo, Margarita, Porter, Gene, Eveland, Suzanne, Frantz-Wattley, Betsy, Kavana, Mike, Addona, George, Sinclair, Peter, Sparrow, Carl, O'Neill, Edward A., Koblan, Ken S., Sitlani, Ayesha, Hubbard, Brian, Fisher, Timothy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918456/
https://ncbi.nlm.nih.gov/pubmed/20458119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M007468
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