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Conjugation to nickel-chelating nanolipoprotein particles increases the potency and efficacy of subunit vaccines to prevent West Nile encephalitis

Subunit antigens are attractive candidates for vaccine development as they are safe, cost-effective, and rapidly produced. Nevertheless, subunit antigens often need to be adjuvanted and/or formulated to produce products with acceptable potency and efficacy. Here we describe a simple method for impro...

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Bibliografiske detaljer
Main Authors: Fischer, Nicholas O., Infante, Ernesto, Ishikawa, Tomohiro, Blanchette, Craig D., Bourne, Nigel, Hoeprich, Paul D., Mason, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918428/
https://ncbi.nlm.nih.gov/pubmed/20509624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100083d
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