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The AZFc region of the Y chromosome: at the crossroads between genetic diversity and male infertility

BACKGROUND: The three azoospermia factor (AZF) regions of the Y chromosome represent genomic niches for spermatogenesis genes. Yet, the most distal region, AZFc, is a major generator of large-scale variation in the human genome. Determining to what extent this variability affects spermatogenesis is...

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Autors principals: Navarro-Costa, Paulo, Gonçalves, João, Plancha, Carlos E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918367/
https://ncbi.nlm.nih.gov/pubmed/20304777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humupd/dmq005
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