The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model

Mutant copper/zinc superoxide dismutase (SOD1)-overexpressing transgenic mice, a mouse model for familial amyotrophic lateral sclerosis (ALS), provides an excellent resource for developing novel therapies for ALS. Several observations suggest that mitochondria-dependent apoptotic signaling, includin...

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Auteurs principaux: Inoue, Haruhisa, Tsukita, Kayoko, Iwasato, Takuji, Suzuki, Yasuyuki, Tomioka, Masanori, Tateno, Minako, Nagao, Masahiro, Kawata, Akihiro, Saido, Takaomi C., Miura, Masayuki, Misawa, Hidemi, Itohara, Shigeyoshi, Takahashi, Ryosuke
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC291829/
https://ncbi.nlm.nih.gov/pubmed/14657037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg634
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