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Distinct Human Papillomavirus Type 16 Methylomes in Cervical Cells at Different Stages of Premalignancy

Human papillomavirus (HPV) gene expression is dramatically altered during cervical carcinogenesis. Because dysregulated genes frequently show abnormal patterns of DNA methylation, we hypothesized that comprehensive mapping of the HPV methylomes in cervical samples at different stages of progression...

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Autors principals: Brandsma, Janet L., Sun, Ying, Lizardi, Paul M., Tuck, David P., Zelterman, Daniel, Haines, G. Kenneth, Martel, Maritza, Harigopal, Malini, Schofield, Kevin, Neapolitano, Matthew
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918277/
https://ncbi.nlm.nih.gov/pubmed/19443004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.03.029
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