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Combinatorial effects of IL-10 and IL-4 determine the progression of hepatic inflammation following murine enteric parasitic infection
Mice lacking the immunoregulatory cytokine, IL-10, develop necrotizing hepatitis following infection with Trichinella spiralis, and inflammation is dependent on migration of intestinally activated CD4(+) T cells into the liver. Hepatic production of IL-4 is elevated in these mice, and we hypothesize...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918232/ https://ncbi.nlm.nih.gov/pubmed/20513001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23576 |
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