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Characterization and Quantitation of Antibody Aggregates by High Mass MALDI Mass Spectrometry

RP-49 Size Exclusion Chromatography (SEC) fractions of therapeutic antibody aggregates were collected and submitted to intact analysis by High-Mass MALDI (Matrix Assisted Laser-Desorption / Ionization) mass spectrometry. SEC fractions were stabilized using MALDI crosslinking (K200 Stabilization Kits...

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Hlavní autoři: Nazabal, A., Weber, J., Wenzel, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association of Biomolecular Resource Facilities 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918159/
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