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Increased Sequence Coverage in Complex Protein Digests by Consecutive, Targeted LC-MSMS Runs with Both CID and ETD
RP-110 Highly complex protein digests cannot be analyzed in one single run as not all tryptic peptides will be triggered with an automated MSMS approach. Additionally, many PTMs are low abundant and therefore often not detected in a first run. However, for a second injection the same sample amount i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918076/ |
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