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Structural changes in the carboxyl terminus of the gap junction protein Connexin40 caused by the interaction with c-Src and Zonula Occludens-1

c-Src can disrupt the Connexin43 (Cx43) and Zonula Occludens-1 (ZO-1) interaction leading to down-regulation of gap junction intercellular communication. Previously, we characterized the interaction of domains from these proteins with the carboxyl terminus of Cx43 (Cx43CT) and found that binding of...

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Main Authors: Bouvier, Denis, Kieken, Fabien, Kellezi, Admir, Sorgen, Paul
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917908/
https://ncbi.nlm.nih.gov/pubmed/18649183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15419060802014347
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