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β-CATENIN MEDIATES INSULIN-LIKE GROWTH FACTOR-I (IGF-I) ACTIONS TO PROMOTE CYCLIN D1 mRNA EXPRESSION, CELL PROLIFERATION AND SURVIVAL IN OLIGODENDROGLIAL CULTURES
By promoting cell proliferation, survival and maturation insulin-like growth factor (IGF)-I is essential to the normal growth and development of the central nervous system. It is clear that IGF-I actions are primarily mediated by the type I IGF receptor (IGF1R), and that phosphoinositide 3 (PI3)-Akt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917840/ https://ncbi.nlm.nih.gov/pubmed/20235220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20984 |
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