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ROLE OF ANTIBODIES IN DEVELOPING DRUGS THAT TARGET G PROTEIN-COUPLED RECEPTOR DIMERS
G protein-coupled receptors (GPCRs) are important molecular targets in drug discovery. These receptors play a pivotal role in physiological signaling pathways and are targeted by nearly 50% of currently available drugs. Mounting evidence suggests that GPCRs form dimers and various studies have shown...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917817/ https://ncbi.nlm.nih.gov/pubmed/20687183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/msj.20199 |
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