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Translational read-through of a nonsense mutation in ATP7A impacts treatment outcome in Menkes disease
Protein translation ends when a stop codon in a gene’s messenger RNA transcript enters the ribosomal A site. Mutations that create premature stop codons (nonsense mutations) typically cause premature translation termination. An alternative outcome, read-through translation (or nonsense suppression),...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917729/ https://ncbi.nlm.nih.gov/pubmed/19194885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21576 |
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