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Helical filaments of human Dmc1 protein on single-stranded DNA: a cautionary tale

Proteins in the RecA/Rad51/RadA family form nucleoprotein filaments on DNA that catalyze a strand exchange reaction as part of homologous genetic recombination. Because of the centrality of this system to many aspects of DNA repair, the generation of genetic diversity, and cancer when this system fa...

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Autores principales: Yu, Xiong, Egelman, Edward H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917623/
https://ncbi.nlm.nih.gov/pubmed/20600108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.049
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