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1α,25-dihydroxyvitamin D(3) acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro

Osteoblasts/osteocytes are the principle sources of fibroblast growth factor 23 (FGF23), a phosphaturic hormone, but the regulation of FGF23 expression during osteoblast development remains uncertain. Because 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and inorganic phosphate (Pi) may act as poten...

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Bibliografiske detaljer
Main Authors: Yamamoto, Ryoko, Minamizaki, Tomoko, Yoshiko, Yuji, Yoshioka, Hirotaka, Tanne, Kazuo, Aubin, Jane E, Maeda, Norihiko
Format: Artigo
Sprog:Inglês
Udgivet: BioScientifica 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917591/
https://ncbi.nlm.nih.gov/pubmed/20530653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0058
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