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1α,25-dihydroxyvitamin D(3) acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro
Osteoblasts/osteocytes are the principle sources of fibroblast growth factor 23 (FGF23), a phosphaturic hormone, but the regulation of FGF23 expression during osteoblast development remains uncertain. Because 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and inorganic phosphate (Pi) may act as poten...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioScientifica
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917591/ https://ncbi.nlm.nih.gov/pubmed/20530653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-10-0058 |
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