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Protein O-mannosylation in animal development and physiology: from human disorders to Drosophila phenotypes

Protein O-mannosylation has a profound effect on the development and physiology of mammalian organisms. Mutations in genes affecting O-mannosyl glycan biosynthesis result in congenital muscular dystrophies. The main pathological mechanism triggered by O-mannosylation defects is a compromised interac...

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Detalhes bibliográficos
Main Authors: Nakamura, Naosuke, Lyalin, Dmitry, Panin, Vladislav M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917527/
https://ncbi.nlm.nih.gov/pubmed/20362685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.03.010
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