Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells

The Chlamydia-secreted protease/proteasome-like activity factor (CPAF) is synthesized as a proenzyme (proCPAF) and requires processing for proteolytic activity. Recent structural studies have further demonstrated that CPAF is a serine protease that can undergo autoprocessing and self-activation in a...

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Bibliographic Details
Main Authors: Chen, Ding, Lei, Lei, Flores, Rhonda, Huang, Zhiwei, Wu, Zhongming, Chai, Jijie, Zhong, Guangming
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917482/
https://ncbi.nlm.nih.gov/pubmed/20510344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.05.008
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