Nalaganje...
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction
RATIONALE: Cardiac fibroblasts are key effector cells in the pathogenesis of cardiac fibrosis. Transforming Growth Factor (TGF)-βSmad3 signaling is activated in the border zone of healing infarcts and induces fibrotic remodeling of the infarcted ventricle contributing to the development of diastolic...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917472/ https://ncbi.nlm.nih.gov/pubmed/20522804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.216101 |
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