Interleukin-1 Receptor Type I Signaling Critically Regulates Infarct Healing and Cardiac Remodeling

The proinflammatory cytokine interleukin (IL)-1 signals exclusively through the type I IL-1 receptor (IL-1RI). IL-1 expression is markedly induced in the infarcted heart; however, its role in cardiac injury and repair remains controversial. We examined the effects of disrupted IL-1 signaling on infa...

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Detalhes bibliográficos
Main Authors: Bujak, Marcin, Dobaczewski, Marcin, Chatila, Khaled, Mendoza, Leonardo H., Li, Na, Reddy, Anilkumar, Frangogiannis, Nikolaos G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438285/
https://ncbi.nlm.nih.gov/pubmed/18535174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070974
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