Gp91(phox )(NOX2) in classically activated microglia exacerbates traumatic brain injury

BACKGROUND: We hypothesized that gp91(phox )(NOX2), a subunit of NADPH oxidase, generates superoxide anion (O(2)(-)) and has a major causative role in traumatic brain injury (TBI). To evaluate the functional role of gp91(phox )and reactive oxygen species (ROS) on TBI, we carried out controlled corti...

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Autors principals: Dohi, Kenji, Ohtaki, Hirokazu, Nakamachi, Tomoya, Yofu, Sachiko, Satoh, Kazue, Miyamoto, Kazuyuki, Song, Dandan, Tsunawaki, Shohko, Shioda, Seiji, Aruga, Tohru
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917406/
https://ncbi.nlm.nih.gov/pubmed/20659322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-41
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