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Deficits in Phosphorylation of GABA(A) Receptors by Intimately Associated Protein Kinase C Activity Underlie Compromised Synaptic Inhibition during Status Epilepticus

Status epilepticus (SE) is a progressive and often lethal human disorder characterized by continuous or rapidly repeating seizures. Of major significance in the pathology of SE are deficits in the functional expression of GABA(A) receptors (GABA(A)Rs), the major sites of fast synaptic inhibition in...

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Detalhes bibliográficos
Main Authors: Terunuma, Miho, Xu, Jianwei, Vithlani, Mansi, Sieghart, Werner, Kittler, Josef, Pangalos, Menelas, Haydon, Philip G., Coulter, Douglas A., Moss, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917223/
https://ncbi.nlm.nih.gov/pubmed/18184780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4346-07.2008
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