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Chemoenzymatic Synthesis of Uridine 5′-Diphospho-2-acetonyl-2-deoxy-α-D-glucose as C(2)-Carbon Isostere of UDP-GlcNAc
[Image: see text] 2-ketoGlc, which is the C(2)-carbon isostere of GlcNAc, is a novel GlcNAc analogue with a ketone group. The corresponding glycosyltransferase donor substrate, UDP-2-ketoGlc, is necessary for synthesizing 2-ketoGlc-containing molecules and is thus highly important for metabolic poly...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917071/ https://ncbi.nlm.nih.gov/pubmed/20384302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo100385p |
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