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CASPASE-1 RECOGNIZES EXTENDED CLEAVAGE SITES IN ITS NATURAL SUBSTRATES

OBJECTIVE: The preferred amino acids in the proteolytic sites have been considered to be similar between caspase-1 and caspase-9, which do not support their differential functions in inflammatory pyroptosis and apoptosis. We attempted to solve this problem. METHODS: We analyzed the flanking 20 amino...

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Dettagli Bibliografici
Autori principali: Shen, Jerry, Yin, Ying, Mai, Jietang, Xiong, Xinyu, Pansuria, Meghana, Liu, Jingshan, Maley, Erin, Saqib, Najam Us, Wang, Hong, Yang, Xiao-Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917068/
https://ncbi.nlm.nih.gov/pubmed/20060974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2009.12.017
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