Structural Characterization of the rod cGMP Phosphodiesterase 6

Rod cGMP phosphodiesterase 6 (PDE6) is a key enzyme of the phototransduction cascade, consisting of PDE6α, PDE6β and two regulatory PDE6γ subunits. PDE6 is membrane-associated through isoprenyl membrane anchors attached to the C-termini of PDE6α and PDE6β and can form a complex with PrBP/δ, an isopr...

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Bibliographic Details
Main Authors: Goc, Anna, Chami, Mohamed, Lodowski, David T., Bosshart, Patrick, Moiseenkova-Bell, Vera, Baehr, Wolfgang, Engel, Andreas, Palczewski, Krzysztof
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917047/
https://ncbi.nlm.nih.gov/pubmed/20600113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.044
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