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Incorporating tumour pathology information into breast cancer risk prediction algorithms

INTRODUCTION: Mutations in BRCA1 and BRCA2 confer high risks of breast cancer and ovarian cancer. The risk prediction algorithm BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) may be used to compute the probabilities of carrying mutations in BRCA1 and BRC...

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Detalhes bibliográficos
Main Authors: Mavaddat, Nasim, Rebbeck, Timothy R, Lakhani, Sunil R, Easton, Douglas F, Antoniou, Antonis C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917017/
https://ncbi.nlm.nih.gov/pubmed/20482762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2576
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